Author Archives: ZARZAR-LAND

What Is CRISPR & How Could It Edit Your DNA? The Gene Machine & What The CRISPR Experiments Mean For Humanity

Above: What Is CRISPR & How Could It Edit Your DNA? The Gene Machine & What The CRISPR Experiments Mean For Humanity.

Gene editing tool CRISPR is everywhere in the news, but what is CRISPR and could it eliminate human diseases?

CRISPR: A Game Changing Genetic Engineering Technique

Have you heard? A revolution has seized the scientific community. Within only a few years, research labs worldwide have adopted a new technology that facilitates making specific changes in the DNA of humans, other animals, and plants.

A new technique that lets scientists edit DNA with ease is transforming science, and raising difficult questions. The DNA editing technique, known as CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats), could revolutionize human gene therapy and genetic engineering because it allows scientists for the first time to make the finest changes to the DNA of human chromosomes with relative ease.

Above: What Is CRISPR & How Could It Edit Your DNA? The Gene Machine & What The CRISPR Experiments Mean For Humanity.

How CRISPR Edits DNA

Every cell in the body carries a copy of genetic code, a blueprint of who we are as humans. CRISPR allows scientists to edit that genetic code with more control than ever before in human history. First, the CRISPR molecule is programmed to search for specific sequences, like mutated ones that cause disease, among the 3 billion letters in the human DNA code. Once the mutation is found, CRISPR unzips the twisted DNA strands and cuts the targeted DNA sequence with its molecular scissors. The body can then repair itself on its own or scientists can patch in a corrected sequence. If done inside an egg, sperm, or embryonic cell, the changes will be passed on to future generations. Thus, with CRISPR, changes can be made more precisely and easily to practically any living thing.

How To Change Our Own Genes: Epigenetics And Gene Manipulation (Genetic Manipulation)

Above: How To Change Our Own Genes: Epigenetics And Gene Manipulation (Genetic Manipulation).

It’s called epigenetics and according to new research, it can influence everything from a human’s weight to a small animal’s propensity to fall in love. And as Anthony tells us, small life changes actually give us control to how these genes are expressed.

Can You Live With Only Half Of Your Brain?

Above: Can You Live With Only Half Of Your Brain?

People have been known to survive with huge pieces of their brains missing, but just which brain parts could we live without? Strange but true: when half a brain is better than a whole brain. The operation known as hemispherectomy, where half the brain is removed, sounds too radical to ever consider, much less perform. However, in the last century, surgeons have performed it hundreds of times for disorders uncontrollable in any other way. Unbelievably, this type of brain surgery where half of your brain is removed has no apparent effect on personality or memory.

ZARZAR MODELS – ZARZAR MODELING AGENCY – Beautiful Fashion Model Elena Uvarova Modeling For The Cover Of FINE Magazine In Beautiful San Diego Southern California


Above: ZARZAR MODELS – ZARZAR MODELING AGENCY – Beautiful Fashion Model Elena Uvarova Modeling For The Cover Of FINE Magazine In Beautiful San Diego Southern California.

ZARZAR MODELING AGENCY best known around the world as ZARZAR MODELS congratulates fashion model Elena Uvarova as she makes the cover of FINE magazine, adding another cover to our ever growing collection of magazine covers. This specific FINE magazine booking (magazine cover and fashion editorial) was done by ZARZAR MODELS in the western United States.

Above: ZARZAR MODELS – ZARZAR MODELING AGENCY – Beautiful Fashion Model Elena Uvarova Modeling For FINE Magazine Fashion Editorials In Beautiful San Diego Southern California.

ZARZAR MODELS is one of the top modeling agencies for women in the United States representing models in print fashion editorials, high fashion runway, film, television commercials, and promotions. The agency represents top models in all of the major fashion cities and counties including Los Angeles, Beverly Hills, Hollywood, Orange County Southern California, San Diego, San Francisco, Las Vegas, Phoenix, Miami, New York, London, Paris, Milan, Sao Paulo, and Tokyo and recruits and represents models throughout the world through its global fashion and modeling network.

http://www.zarzarmodels.com/

Why Invest In Gilead Sciences Stock?

Above: Why Invest In Gilead Sciences Stock?

An estimated 37 million people around the world have HIV. Around 17 million of them are taking prescription drugs to treat their condition, with the majority of those HIV drugs having been developed by Gilead Sciences. In fact, the total global HIV drug market totals more than $20 billion annually, with Gilead Sciences claiming the highest market share of any HIV drug maker in the entire world. This big biotech company had eight HIV drugs combine for sales of more than $12.8 billion in 2016, with Gilead’s Truvada being the top selling HIV drug in the world.

While the growth of Gilead Sciences was due primarily to its HIV franchise for much of the company’s history, in recent years its hepatitis C virus (HCV) drugs have made even more money. In 2016, Gilead’s hepatitis C virus (HCV) drugs combined to generate revenue of $14.8 billion. However, hepatitis C virus (HCV) sales are falling significantly, partially because of increased competition but resulting even more from lower patient starts, as the sickest hepatitis C virus (HCV) patients have already been cured by Gilead Sciences.

Finding The Cure For Hepatitis C

Throughout the course of human history, there have been plenty of drugs developed to treat diseases. However, there haven’t been nearly as many drugs that actually cured a disease. That is especially the case for a chronic disease like hepatitis C, which affects millions of people across the world. But Gilead Sciences changed history by introducing a cure for hepatitis C.

In December 2013, the U.S. Food and Drug Administration (FDA) approved Sovaldi, and Gilead quickly launched the drug. To say that Sovaldi was successful would be a huge understatement. The drug enjoyed the fastest launch ever, and in its first quarter, Sovaldi became a mega blockbuster, generating sales of $2.27 billion.

Gilead Sciences followed up on that success with Harvoni, which launched in the fourth quarter of 2014. Harvoni is a combination of Sovaldi and another Gilead drug, Ledipasvir. In 2015, sales for Harvoni reached a whopping $13.9 billion, with Sovaldi adding another $5.3 billion. However, there is a big problem for a biotech or pharmaceutical company that sells products that cure a disease. After a period of time, there aren’t as many patients to use the products, and that is exactly what happened with Gilead Sciences. The company became a victim of its own success. Sales for its hepatitis C drugs are falling, weighing down Gilead’s overall revenue and earnings.

Gilead’s best hope now for returning to growth is to make one or more biotech acquisitions. The company has indicated that’s exactly what it plans to do in the near future. The good news is that Gilead Sciences has a pretty good track record of making deals. In 2011, Gilead Sciences spent $11 billion to buy Pharmasset, which owned the drug that would eventually be called Sovaldi, a drug that would eventually cure hepatitis C for millions of people suffering from the disease around the world, and making the shareholders of Gilead Sciences very wealthy in the process.